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Caspase-2 deficiency accelerates chemically induced liver cancer in mice
Aberrant cell death/survival has a critical role in the development of hepatocellular carcinoma (HCC). Caspase-2, a cell death protease, limits oxidative stress and chromosomal instability. To study its role in reactive oxygen species (ROS) and DNA damage-induced liver cancer, we assessed diethylnit...
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| Publicado no: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5041200/ https://ncbi.nlm.nih.gov/pubmed/27518436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.81 |
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