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Age-related proteostasis and metabolic alterations in Caspase-2-deficient mice

Ageing is a complex biological process for which underlying biochemical changes are still largely unknown. We performed comparative profiling of the cellular proteome and metabolome to understand the molecular basis of ageing in Caspase-2-deficient (Casp2(−/−)) mice that are a model of premature age...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wilson, C H, Shalini, S, Filipovska, A, Richman, T R, Davies, S, Martin, S D, McGee, S L, Puccini, J, Nikolic, A, Dorstyn, L, Kumar, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669765/
https://ncbi.nlm.nih.gov/pubmed/25611376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.567
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