Age-related proteostasis and metabolic alterations in Caspase-2-deficient mice

Ageing is a complex biological process for which underlying biochemical changes are still largely unknown. We performed comparative profiling of the cellular proteome and metabolome to understand the molecular basis of ageing in Caspase-2-deficient (Casp2(−/−)) mice that are a model of premature age...

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Библиографические подробности
Опубликовано в: :Cell Death Dis
Главные авторы: Wilson, C H, Shalini, S, Filipovska, A, Richman, T R, Davies, S, Martin, S D, McGee, S L, Puccini, J, Nikolic, A, Dorstyn, L, Kumar, S
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2015
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669765/
https://ncbi.nlm.nih.gov/pubmed/25611376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.567
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