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Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice
Caspase-2 has been implicated in apoptosis and in non-apoptotic processes such as cell cycle regulation, tumor suppression and ageing. Using caspase-2 knockout (casp2(−/−)) mice, we show here that the putative anti-ageing role of this caspase is due in part to its involvement in the stress response...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392626/ https://ncbi.nlm.nih.gov/pubmed/22343713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.13 |
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