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Nuclear cyclin D1: An oncogenic driver in human cancer
Perturbations in the regulation of the core cell cycle machinery are frequently observed in human cancers. Cyclin D1 which functions as a mitogenic sensor and allosteric activator of CDK4/6, is one of the more frequently altered cell cycle regulators in cancers. Cyclin D1 is frequently overexpressed...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874239/ https://ncbi.nlm.nih.gov/pubmed/19415697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21791 |
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