Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1–dependent cellular transformation

GSK-3β-dependent phosphorylation of cyclin D1 at Thr-286 promotes the nuclear-to-cytoplasmic redistribution of cyclin D1 during S phase of the cell cycle, but how phosphorylation regulates redistribution has not been resolved. For example, phosphorylation of nuclear cyclin D1 could increase its rate...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Alt, Jodi R., Cleveland, John L., Hannink, Mark, Diehl, J. Alan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2000
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317128/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11124803/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.854900
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