Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

Recent studies identified a short peptide motif that serves as a docking site for cyclin/cyclin-dependent kinase (cdk) 2 complexes(.) Peptides containing this motif block the phosphorylation of substrates by cyclin A/cdk2 or cyclin E/cdk2. Here we report that cell membrane-permeable forms of such pe...

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Detalhes bibliográficos
Main Authors: Chen, Ying-Nan P., Sharma, Sushil K., Ramsey, Timothy M., Jiang, Li, Martin, Mary S., Baker, Kayla, Adams, Peter D., Bair, Kenneth W., Kaelin, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16331/
https://ncbi.nlm.nih.gov/pubmed/10200261
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