Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

Recent studies identified a short peptide motif that serves as a docking site for cyclin/cyclin-dependent kinase (cdk) 2 complexes(.) Peptides containing this motif block the phosphorylation of substrates by cyclin A/cdk2 or cyclin E/cdk2. Here we report that cell membrane-permeable forms of such pe...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Chen, Ying-Nan P., Sharma, Sushil K., Ramsey, Timothy M., Jiang, Li, Martin, Mary S., Baker, Kayla, Adams, Peter D., Bair, Kenneth W., Kaelin, William G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16331/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10200261/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.8.4325
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