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Cyclin D1, Cancer Progression and Opportunities in Cancer Treatment
Mammalian cells encode three D cyclins (D1, D2 and D3) that coordinately function as allosteric regulators of cyclin dependent kinase 4 and 6 (CDK4/CDK6) to regulate cell cycle transition from G1 to S phase. Cyclin expression, accumulation and degradation, as well as assembly and activation of CDK4/...
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| 出版年: | J Mol Med (Berl) |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5145738/ https://ncbi.nlm.nih.gov/pubmed/27695879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-016-1475-3 |
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