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Cyclin D1, Cancer Progression and Opportunities in Cancer Treatment
Mammalian cells encode three D cyclins (D1, D2 and D3) that coordinately function as allosteric regulators of cyclin dependent kinase 4 and 6 (CDK4/CDK6) to regulate cell cycle transition from G1 to S phase. Cyclin expression, accumulation and degradation, as well as assembly and activation of CDK4/...
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| Publicado no: | J Mol Med (Berl) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5145738/ https://ncbi.nlm.nih.gov/pubmed/27695879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-016-1475-3 |
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