A carregar...
Disruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesis
Cyclin D1 levels are maintained at steady state by phosphorylation-dependent nuclear export and polyubiquitination by the SCF(FBX4-αB crystallin) E3 ligase. Inhibition of cyclin D1 proteolysis has been implicated as a causative factor leading to its overexpression in carcinomas of the breast and eso...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3733559/ https://ncbi.nlm.nih.gov/pubmed/17724472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210738 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|