Pyridine and pyrimidine analogs of acetaminophen as inhibitors of lipid peroxidation and cyclooxygenase and lipoxygenase catalysis

Herein we report an investigation of the efficacy of pyridine and pyrimidine analogs of acetaminophen (ApAP) as peroxyl radical-trapping antioxidants and inhibitors of enzyme-catalyzed lipid peroxidation by cyclooxygenases (COX) and lipoxygenases (LOX). In inhibited autoxidations we find that ApAP,...

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Detaylı Bibliyografya
Asıl Yazarlar: Nam, Tae-gyu, Nara, Susheel J., Zagol-Ikapitte, Irène, Cooper, Thomas, Valgimigli, Luca, Oates, John A., Porter, Ned A., Boutaud, Olivier, Pratt, Derek A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873786/
https://ncbi.nlm.nih.gov/pubmed/20024105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b912528k
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