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Control of oxygenation in lipoxygenase and cyclooxygenase catalysis

Lipoxygenases (LOX) and cyclooxygenases (COX) react an achiral polyunsaturated fatty acid with oxygen to form a chiral peroxide product of high regio- and stereochemical purity. Both enzymes employ free radical chemistry reminiscent of hydrocarbon autoxidation but execute efficient control during ca...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schneider, Claus, Pratt, Derek A., Porter, Ned A., Brash, Alan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692746/
https://ncbi.nlm.nih.gov/pubmed/17524979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2007.04.007
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