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Secondary structure of Huntingtin amino-terminal region
Huntington's disease (HD) is a genetic neurodegenerative disorder resulting from polyglutamine (polyQ) expansion (> 36Q) within first exon of Huntingtin (Htt) protein. Here we applied X-ray crystallography to determine the secondary structure of the first exon (EX1) of Htt-17Q. The structure...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863341/ https://ncbi.nlm.nih.gov/pubmed/19748341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.08.002 |
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