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Refinement by shifting secondary structure elements improves sequence alignments

Constructing a model of a query protein based on its alignment to a homolog with experimentally determined spatial structure (the template) is still the most reliable approach to structure prediction. Alignment errors are the main bottleneck for homology modeling when the query is distantly related...

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Bibliografski detalji
Izdano u:Proteins
Glavni autori: Tong, Jing, Pei, Jimin, Otwinowski, Zbyszek, Grishin, Nick V.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501258/
https://ncbi.nlm.nih.gov/pubmed/25546158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24746
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