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Refinement by shifting secondary structure elements improves sequence alignments
Constructing a model of a query protein based on its alignment to a homolog with experimentally determined spatial structure (the template) is still the most reliable approach to structure prediction. Alignment errors are the main bottleneck for homology modeling when the query is distantly related...
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| Publicado no: | Proteins |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4501258/ https://ncbi.nlm.nih.gov/pubmed/25546158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24746 |
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