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Refinement by shifting secondary structure elements improves sequence alignments
Constructing a model of a query protein based on its alignment to a homolog with experimentally determined spatial structure (the template) is still the most reliable approach to structure prediction. Alignment errors are the main bottleneck for homology modeling when the query is distantly related...
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| Опубликовано в: : | Proteins |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4501258/ https://ncbi.nlm.nih.gov/pubmed/25546158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24746 |
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