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The 2.2‐Angstrom resolution crystal structure of the carboxy‐terminal region of ataxin‐3

An expansion of polyglutamine (polyQ) sequence in ataxin‐3 protein causes spinocerebellar ataxia type 3, an inherited neurodegenerative disorder. The crystal structure of the polyQ‐containing carboxy‐terminal fragment of human ataxin‐3 was solved at 2.2‐Å resolution. The Atxn3 carboxy‐terminal fragm...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Zhemkov, Vladimir A., Kulminskaya, Anna A., Bezprozvanny, Ilya B., Kim, Meewhi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794786/
https://ncbi.nlm.nih.gov/pubmed/27047745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12029
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