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The 2.2‐Angstrom resolution crystal structure of the carboxy‐terminal region of ataxin‐3

An expansion of polyglutamine (polyQ) sequence in ataxin‐3 protein causes spinocerebellar ataxia type 3, an inherited neurodegenerative disorder. The crystal structure of the polyQ‐containing carboxy‐terminal fragment of human ataxin‐3 was solved at 2.2‐Å resolution. The Atxn3 carboxy‐terminal fragm...

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Bibliografiske detaljer
Udgivet i:FEBS Open Bio
Main Authors: Zhemkov, Vladimir A., Kulminskaya, Anna A., Bezprozvanny, Ilya B., Kim, Meewhi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794786/
https://ncbi.nlm.nih.gov/pubmed/27047745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12029
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