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Rac1 targeting suppresses p53 deficiency–mediated lymphomagenesis
Mutation of the p53 tumor suppressor is associated with disease progression, therapeutic resistance, and poor prognosis in patients with lymphoid malignancies and can occur in approximately 50% of Burkitt lymphomas. Thus, new therapies are needed to specifically target p53-deficient lymphomas with i...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858481/ https://ncbi.nlm.nih.gov/pubmed/20179179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-202440 |
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