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Rac1 targeting suppresses p53 deficiency–mediated lymphomagenesis

Mutation of the p53 tumor suppressor is associated with disease progression, therapeutic resistance, and poor prognosis in patients with lymphoid malignancies and can occur in approximately 50% of Burkitt lymphomas. Thus, new therapies are needed to specifically target p53-deficient lymphomas with i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bosco, Emily E., Ni, Wenjun, Wang, Lei, Guo, Fukun, Johnson, James F., Zheng, Yi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858481/
https://ncbi.nlm.nih.gov/pubmed/20179179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-202440
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