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Rac1 targeting suppresses p53 deficiency–mediated lymphomagenesis
Mutation of the p53 tumor suppressor is associated with disease progression, therapeutic resistance, and poor prognosis in patients with lymphoid malignancies and can occur in approximately 50% of Burkitt lymphomas. Thus, new therapies are needed to specifically target p53-deficient lymphomas with i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858481/ https://ncbi.nlm.nih.gov/pubmed/20179179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-202440 |
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