Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

During carcinogenesis of pancreatic islets in transgenic mice, an angiogenic switch activates the quiescent vasculature. Paradoxically, vascular endothelial growth factor (VEGF) and its receptors are expressed constitutively. Nevertheless, a synthetic inhibitor (SU5416) of VEGF signalling impairs an...

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Detaylı Bibliyografya
Asıl Yazarlar: Bergers, Gabriele, Brekken, Rolf, McMahon, Gerald, Vu, Thiennu H., Itoh, Takeshi, Tamaki, Kazuhiko, Tanzawa, Kazuhiko, Thorpe, Philip, Itohara, Shigeyoshi, Werb, Zena, Hanahan, Douglas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2000
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852586/
https://ncbi.nlm.nih.gov/pubmed/11025665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/35036374
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