Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

During carcinogenesis of pancreatic islets in transgenic mice, an angiogenic switch activates the quiescent vasculature. Paradoxically, vascular endothelial growth factor (VEGF) and its receptors are expressed constitutively. Nevertheless, a synthetic inhibitor (SU5416) of VEGF signalling impairs an...

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Bibliografski detalji
Glavni autori: Bergers, Gabriele, Brekken, Rolf, McMahon, Gerald, Vu, Thiennu H., Itoh, Takeshi, Tamaki, Kazuhiko, Tanzawa, Kazuhiko, Thorpe, Philip, Itohara, Shigeyoshi, Werb, Zena, Hanahan, Douglas
Format: Artigo
Jezik:Inglês
Izdano: 2000
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852586/
https://ncbi.nlm.nih.gov/pubmed/11025665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/35036374
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