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Structural basis underlying the dual gate properties of KcsA
KcsA is a prokaryotic pH-dependent potassium (K) channel. Its activation, by a decrease in the intracellular pH, is coupled with its subsequent inactivation, but the underlying mechanisms remain elusive. Here, we have investigated the conformational changes and equilibrium of KcsA by using solution...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852003/ https://ncbi.nlm.nih.gov/pubmed/20212150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911270107 |
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