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Intrinsic flexibility and gating mechanism of the potassium channel KcsA

The gating mechanism of the potassium channel KcsA was studied by normal mode analysis. The results provided an atomic description of the locations of the pivot points and the motional features of key structural elements in the gating process. Two pivot points were found in the motions of the inner...

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Autori principali: Shen, Yufeng, Kong, Yifei, Ma, Jianpeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC122300/
https://ncbi.nlm.nih.gov/pubmed/11842204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042650399
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