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Intrinsic flexibility and gating mechanism of the potassium channel KcsA

The gating mechanism of the potassium channel KcsA was studied by normal mode analysis. The results provided an atomic description of the locations of the pivot points and the motional features of key structural elements in the gating process. Two pivot points were found in the motions of the inner...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Shen, Yufeng, Kong, Yifei, Ma, Jianpeng
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2002
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122300/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11842204/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.042650399
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