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Rearrangements in the KcsA Cytoplasmic Domain Underlie Its Gating

A change of cytosolic pH 7 to 4 opens the bacterial potassium channel KcsA. However, the overall gating mechanism leading to channel opening, especially the contribution of the cytoplasmic domain, remains unsolved. Here we report that deletion of the cytoplasmic domain resulted in changes in channel...

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Bibliografske podrobnosti
Main Authors: Hirano, Minako, Takeuchi, Yuko, Aoki, Takaaki, Yanagida, Toshio, Ide, Toru
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823519/
https://ncbi.nlm.nih.gov/pubmed/19959477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.084368
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