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Structural basis underlying the dual gate properties of KcsA
KcsA is a prokaryotic pH-dependent potassium (K) channel. Its activation, by a decrease in the intracellular pH, is coupled with its subsequent inactivation, but the underlying mechanisms remain elusive. Here, we have investigated the conformational changes and equilibrium of KcsA by using solution...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852003/ https://ncbi.nlm.nih.gov/pubmed/20212150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911270107 |
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