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Implications of the HIV-1 Rev dimer structure at 3.2 Å resolution for multimeric binding to the Rev response element
HIV-1 Rev is a small regulatory protein that mediates the nuclear export of viral mRNAs, an essential step in the HIV replication cycle. In this process Rev oligomerizes in association with a highly structured RNA motif, the Rev response element. Crystallographic studies of Rev have been hampered by...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851902/ https://ncbi.nlm.nih.gov/pubmed/20231488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914946107 |
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