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Generation and characterization of a chimeric rabbit/human Fab for co-crystallization of HIV-1 Rev

Rev is a key regulatory protein of HIV-1. Its function is to bind to viral transcripts and effect export from the nucleus of unspliced mRNA thereby allowing the synthesis of structural proteins. Despite its evident importance, the structure of Rev has remained unknown, primarily because Rev’s procli...

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Autors principals: Stahl, Stephen J., Watts, Norman R., Rader, Christoph, Dimattia, Michael A., Mage, Rose G., Palmer, Ira, Kaufman, Joshua D., Grimes, Jonathan M., Stuart, David I., Steven, Alasdair C., Wingfield, Paul T.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851401/
https://ncbi.nlm.nih.gov/pubmed/20138059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.01.061
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