The Structure of HIV-1 Rev Filaments Suggests a Bilateral Model for Rev-RRE Assembly

HIV-1 Rev protein mediates the nuclear export of viral RNA genomes. To do so, Rev oligomerizes cooperatively onto an RNA motif, the Rev-response element (RRE), forming a complex that engages with the host nuclear export machinery. To better understand Rev oligomerization, we determined four crystal...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Structure
Auteurs principaux: DiMattia, Michael A., Watts, Norman R., Cheng, Naiqian, Huang, Rick, Heymann, J. Bernard, Grimes, Jonathan M., Wingfield, Paul T., Stuart, David I., Steven, Alasdair C.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938712/
https://ncbi.nlm.nih.gov/pubmed/27265851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.04.015
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires