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The Structure of HIV-1 Rev Filaments Suggests a Bilateral Model for Rev-RRE Assembly
HIV-1 Rev protein mediates the nuclear export of viral RNA genomes. To do so, Rev oligomerizes cooperatively onto an RNA motif, the Rev-response element (RRE), forming a complex that engages with the host nuclear export machinery. To better understand Rev oligomerization, we determined four crystal...
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| Pubblicato in: | Structure |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4938712/ https://ncbi.nlm.nih.gov/pubmed/27265851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.04.015 |
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