Antigenic Switching of Hepatitis B Virus by Alternative Dimerization of the Capsid Protein

Chronic Hepatitis B virus (HBV) infection afflicts millions worldwide with cirrhosis and liver cancer. HBV e-antigen (HBeAg), a clinical marker for disease severity, is a non-particulate variant of the protein (core antigen, HBcAg) that forms the building-blocks of capsids. HBeAg is not required for...

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Main Authors: DiMattia, Michael A., Watts, Norman R., Stahl, Stephen J., Grimes, Jonathan M., Steven, Alasdair C., Stuart, David I., Wingfield, Paul T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544974/
https://ncbi.nlm.nih.gov/pubmed/23219881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.10.017
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