Molecular basis for the high degree of antigenic cross reactivity between hepatitis B virus capsids (HBcAg) and subunits: Insights into the enigmatic nature of e-antigen

The Hepatitis B Virus (HBV) core gene codes for two closely related antigens: a 21-kDa protein which forms dimers that assemble as multi-megadalton capsids, and a 17-kDa protein which also forms dimers but that do not assemble. The proteins, respectively referred to as core and e-antigen, share a se...

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Bibliographic Details
Main Authors: Watts, Norman R., Vethanayagam, Joe G., Ferns, R. Bridget, Tedder, Richard S., Harris, Audray, Stahl, Stephen J., Steven, Alasdair C., Wingfield, Paul T.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860019/
https://ncbi.nlm.nih.gov/pubmed/20307545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.026
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