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Assessing Sensitivity to Antibacterial Topoisomerase II Inhibitors

Both prokaryotes and eukaryotes have two major classes of topoisomerases that make transient single- or double-strand cuts in DNA. While these enzymes play critical roles in cellular processes, they are also important targets of therapeutic agents. This unit describes assays to use in characterizing...

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Autores principales: Morgan-Linnell, Sonia K., Hiasa, Hiroshi, Zechiedrich, Lynn, Nitiss, John L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2850120/
https://ncbi.nlm.nih.gov/pubmed/21948169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471141755.ph0313s39
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