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Contributions of the Combined Effects of Topoisomerase Mutations toward Fluoroquinolone Resistance in Escherichia coli

In defined, isogenic strains, at least three mutations, two of which must be in gyrA, were required to exceed the CLSI breakpoint for fluoroquinolone resistance. Strains with double mutations in both gyrA and parC had even higher MICs of fluoroquinolones than strains with totals of three mutations.

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Bibliografski detalji
Glavni autori: Morgan-Linnell, Sonia K., Zechiedrich, Lynn
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151436/
https://ncbi.nlm.nih.gov/pubmed/17682104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00647-07
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