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Contributions of the Combined Effects of Topoisomerase Mutations toward Fluoroquinolone Resistance in Escherichia coli

In defined, isogenic strains, at least three mutations, two of which must be in gyrA, were required to exceed the CLSI breakpoint for fluoroquinolone resistance. Strains with double mutations in both gyrA and parC had even higher MICs of fluoroquinolones than strains with totals of three mutations.

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Detaylı Bibliyografya
Asıl Yazarlar: Morgan-Linnell, Sonia K., Zechiedrich, Lynn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151436/
https://ncbi.nlm.nih.gov/pubmed/17682104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00647-07
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