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Role of Efflux Pumps and Topoisomerase Mutations in Fluoroquinolone Resistance in Campylobacter jejuni and Campylobacter coli

Point mutations in the topoisomerase (DNA gyrase A) gene are known to be associated with fluoroquinolone resistance in Campylobacter. Recent studies have shown that an efflux pump encoded by cmeABC is also involved in decreased susceptibilities to fluoroquinolones, as well as other antimicrobials. G...

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Bibliografiske detaljer
Main Authors: Ge, Beilei, McDermott, Patrick F., White, David G., Meng, Jianghong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196287/
https://ncbi.nlm.nih.gov/pubmed/16048946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.8.3347-3354.2005
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