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Mechanisms Accounting for Fluoroquinolone Resistance in Escherichia coli Clinical Isolates

Fluoroquinolone MICs are increased through the acquisition of chromosomal mutations in the genes encoding gyrase (gyrA and gyrB) and topoisomerase IV (parC and parE), increased levels of the multidrug efflux pump AcrAB, and the plasmid-borne genes aac(6′)-Ib-cr and the qnr variants in Escherichia co...

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Bibliografiske detaljer
Main Authors: Morgan-Linnell, Sonia K., Becnel Boyd, Lauren, Steffen, David, Zechiedrich, Lynn
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612180/
https://ncbi.nlm.nih.gov/pubmed/18838592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00665-08
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