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Mechanisms Accounting for Fluoroquinolone Resistance in Escherichia coli Clinical Isolates

Fluoroquinolone MICs are increased through the acquisition of chromosomal mutations in the genes encoding gyrase (gyrA and gyrB) and topoisomerase IV (parC and parE), increased levels of the multidrug efflux pump AcrAB, and the plasmid-borne genes aac(6′)-Ib-cr and the qnr variants in Escherichia co...

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Detalhes bibliográficos
Main Authors: Morgan-Linnell, Sonia K., Becnel Boyd, Lauren, Steffen, David, Zechiedrich, Lynn
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612180/
https://ncbi.nlm.nih.gov/pubmed/18838592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00665-08
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