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Targeting DNA topoisomerase II in cancer chemotherapy
Recent molecular studies have greatly expanded the biological contexts where Top2 plays critical roles, including DNA replication, transcription and chromosome segregation. Although the biological functions of Top2 are important for insuring genomic integrity, the ability to interfere with Top2 and...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748742/ https://ncbi.nlm.nih.gov/pubmed/19377506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2607 |
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