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Yeast recombination pathways triggered by topoisomerase II-mediated DNA breaks

Topoisomerase II is a ubiquitous enzyme that removes knots and tangles from the genetic material by generating transient double-strand DNA breaks. While the enzyme cannot perform its essential cellular functions without cleaving DNA, this scission activity is inherently dangerous to chromosomal inte...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sabourin, Michelle, Nitiss, John L., Nitiss, Karin C., Tatebayashi, Kazuo, Ikeda, Hideo, Osheroff, Neil
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2003
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC169887/
https://ncbi.nlm.nih.gov/pubmed/12888496
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