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Natural Products as Topoisomerase II Poisons: Effects of Thymoquinone on DNA Cleavage Mediated by Human Topoisomerase IIα

[Image: see text] The seeds of Nigella sativa (often referred to as black seed) have long been utilized as a medicinal herb in Middle Eastern, Northern African, and Indian cultures. Historically, black seed has been used to treat a variety of illnesses associated with inflammation. More recent studi...

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Detalhes bibliográficos
Main Authors: Ashley, Rachel E., Osheroff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033629/
https://ncbi.nlm.nih.gov/pubmed/24650156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx400453v
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