Topoisomerase II Alpha and Responsiveness of Breast Cancer to Adjuvant Chemotherapy

BACKGROUND: Amplification or deletion of the topoisomerase II alpha (TOP2A) gene in breast cancers has been postulated to be more closely associated with responsiveness to anthracycline-containing chemotherapy than amplification of the human epidermal growth factor receptor type 2 (HER2) gene. METHO...

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Main Authors: O’Malley, F. P., Chia, S., Tu, D., Shepherd, L. E., Levine, M. N., Bramwell, V. H., Andrulis, I. L., Pritchard, K. I.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677575/
https://ncbi.nlm.nih.gov/pubmed/19401546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djp067
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