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DNA topoisomerase II and its growing repertoire of biological functions

DNA topoisomerases are enzymes that disentangle the topological problems that arise from double stranded DNA. Many of these can be solved by the generation of either single or double strand breaks. However, where there is a clear requirement to alter DNA topology by introducing transient double stra...

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Bibliografiske detaljer
Hovedforfatter: Nitiss, John L.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730144/
https://ncbi.nlm.nih.gov/pubmed/19377505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2608
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