Yüklüyor......
High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis
We present a method that harnesses massively parallel DNA synthesis and sequencing for the high-throughput functional analysis of regulatory sequences at single-nucleotide resolution. As a proof of concept, we quantitatively assayed the effects of all possible single-nucleotide mutations for three b...
Kaydedildi:
| Asıl Yazarlar: | , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849652/ https://ncbi.nlm.nih.gov/pubmed/19915551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1589 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|