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Modularity and interactions in the genetics of gene expression

Understanding the effect of genetic sequence variation on phenotype is a major challenge that lies at the heart of genetics. We developed GOLPH (GenOmic Linkage to PHenotype), a statistical method to identify genetic interactions, and used it to characterize the landscape of genetic interactions bet...

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Detalhes bibliográficos
Main Authors: Litvin, Oren, Causton, Helen C., Chen, Bo-Juen, Pe'er, Dana
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672504/
https://ncbi.nlm.nih.gov/pubmed/19223586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810208106
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