Interferon α/β enhances the cytotoxic response of MEK inhibition in melanoma

Drugs that inhibit the MAPK pathway have therapeutic benefit in melanoma, but responses vary between patients, for reasons that are still largely unknown. Here we aim at explaining this variability using pre- and post-MEK inhibition transcriptional profiles in a panel of melanoma cell-lines. We foun...

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Bibliografski detalji
Izdano u:Mol Cell
Glavni autori: Litvin, Oren, Schwartz, Sarit, Wan, Zhenmao, Schild, Tanya, Rocco, Mark, Oh, Nul Loren, Chen, Bo-Juen, Goddard, Noel, Pratilas, Christine, Pe’er, Dana
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355234/
https://ncbi.nlm.nih.gov/pubmed/25684207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.12.030
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