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Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution
The majority of common variants associated with common diseases, as well as an unknown proportion of causal mutations for rare diseases, fall in noncoding regions of the genome. Although catalogs of noncoding regulatory elements are steadily improving, we have a limited understanding of the function...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6687891/ https://ncbi.nlm.nih.gov/pubmed/31395865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11526-w |
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