Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia

MicroRNA (miRNA)-17-92 cluster (miR-17-92), containing seven individual miRNAs, is frequently amplified and overexpressed in lymphomas and various solid tumors. We have found that it is also frequently amplified and the miRNAs are aberrantly overexpressed in mixed lineage leukemia (MLL)-rearranged a...

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Detalhes bibliográficos
Main Authors: Mi, Shuangli, Li, Zejuan, Chen, Ping, He, Chunjiang, Cao, Donglin, Elkahloun, Abdel, Lu, Jun, Pelloso, Luis A., Wunderlich, Mark, Huang, Hao, Luo, Roger T., Sun, Miao, He, Miao, Neilly, Mary Beth, Zeleznik-Le, Nancy J., Thirman, Michael J., Mulloy, James C., Liu, Paul P., Rowley, Janet D., Chen, Jianjun
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840429/
https://ncbi.nlm.nih.gov/pubmed/20133587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914900107
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