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Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia

MicroRNA (miRNA)-17-92 cluster (miR-17-92), containing seven individual miRNAs, is frequently amplified and overexpressed in lymphomas and various solid tumors. We have found that it is also frequently amplified and the miRNAs are aberrantly overexpressed in mixed lineage leukemia (MLL)-rearranged a...

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Bibliografische gegevens
Hoofdauteurs: Mi, Shuangli, Li, Zejuan, Chen, Ping, He, Chunjiang, Cao, Donglin, Elkahloun, Abdel, Lu, Jun, Pelloso, Luis A., Wunderlich, Mark, Huang, Hao, Luo, Roger T., Sun, Miao, He, Miao, Neilly, Mary Beth, Zeleznik-Le, Nancy J., Thirman, Michael J., Mulloy, James C., Liu, Paul P., Rowley, Janet D., Chen, Jianjun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840429/
https://ncbi.nlm.nih.gov/pubmed/20133587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914900107
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