Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia

MicroRNA (miRNA)-17-92 cluster (miR-17-92), containing seven individual miRNAs, is frequently amplified and overexpressed in lymphomas and various solid tumors. We have found that it is also frequently amplified and the miRNAs are aberrantly overexpressed in mixed lineage leukemia (MLL)-rearranged a...

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Библиографические подробности
Главные авторы: Mi, Shuangli, Li, Zejuan, Chen, Ping, He, Chunjiang, Cao, Donglin, Elkahloun, Abdel, Lu, Jun, Pelloso, Luis A., Wunderlich, Mark, Huang, Hao, Luo, Roger T., Sun, Miao, He, Miao, Neilly, Mary Beth, Zeleznik-Le, Nancy J., Thirman, Michael J., Mulloy, James C., Liu, Paul P., Rowley, Janet D., Chen, Jianjun
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2010
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840429/
https://ncbi.nlm.nih.gov/pubmed/20133587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914900107
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