Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia

MicroRNA (miRNA)-17-92 cluster (miR-17-92), containing seven individual miRNAs, is frequently amplified and overexpressed in lymphomas and various solid tumors. We have found that it is also frequently amplified and the miRNAs are aberrantly overexpressed in mixed lineage leukemia (MLL)-rearranged a...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Mi, Shuangli, Li, Zejuan, Chen, Ping, He, Chunjiang, Cao, Donglin, Elkahloun, Abdel, Lu, Jun, Pelloso, Luis A., Wunderlich, Mark, Huang, Hao, Luo, Roger T., Sun, Miao, He, Miao, Neilly, Mary Beth, Zeleznik-Le, Nancy J., Thirman, Michael J., Mulloy, James C., Liu, Paul P., Rowley, Janet D., Chen, Jianjun
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2010
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840429/
https://ncbi.nlm.nih.gov/pubmed/20133587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914900107
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