Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia

MicroRNA (miRNA)-17-92 cluster (miR-17-92), containing seven individual miRNAs, is frequently amplified and overexpressed in lymphomas and various solid tumors. We have found that it is also frequently amplified and the miRNAs are aberrantly overexpressed in mixed lineage leukemia (MLL)-rearranged a...

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Bibliographic Details
Main Authors: Mi, Shuangli, Li, Zejuan, Chen, Ping, He, Chunjiang, Cao, Donglin, Elkahloun, Abdel, Lu, Jun, Pelloso, Luis A., Wunderlich, Mark, Huang, Hao, Luo, Roger T., Sun, Miao, He, Miao, Neilly, Mary Beth, Zeleznik-Le, Nancy J., Thirman, Michael J., Mulloy, James C., Liu, Paul P., Rowley, Janet D., Chen, Jianjun
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840429/
https://ncbi.nlm.nih.gov/pubmed/20133587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914900107
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