Mosaic HIV-1 Vaccines Expand the Breadth and Depth of Cellular Immune Responses in Rhesus Monkeys

The worldwide diversity of HIV-1 presents an unprecedented challenge for vaccine development 1-2. Antigens derived from natural HIV-1 sequences have elicited only limited breadth of cellular immune responses in nonhuman primate studies and clinical trials to date. Polyvalent “mosaic” antigens, in co...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Barouch, Dan H., O'Brien, Kara L., Simmons, Nathaniel L., King, Sharon L., Abbink, Peter, Maxfield, Lori F., Sun, Ying-Hua, La Porte, Annalena, Riggs, Ambryice M., Lynch, Diana M., Clark, Sarah L., Backus, Katherine, Perry, James R., Seaman, Michael S., Carville, Angela, Mansfield, Keith G., Szinger, James J., Fischer, Will, Muldoon, Mark, Korber, Bette
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834868/
https://ncbi.nlm.nih.gov/pubmed/20173752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2089
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