Mosaic HIV-1 Vaccines Expand the Breadth and Depth of Cellular Immune Responses in Rhesus Monkeys

The worldwide diversity of HIV-1 presents an unprecedented challenge for vaccine development 1-2. Antigens derived from natural HIV-1 sequences have elicited only limited breadth of cellular immune responses in nonhuman primate studies and clinical trials to date. Polyvalent “mosaic” antigens, in co...

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Detaylı Bibliyografya
Asıl Yazarlar: Barouch, Dan H., O'Brien, Kara L., Simmons, Nathaniel L., King, Sharon L., Abbink, Peter, Maxfield, Lori F., Sun, Ying-Hua, La Porte, Annalena, Riggs, Ambryice M., Lynch, Diana M., Clark, Sarah L., Backus, Katherine, Perry, James R., Seaman, Michael S., Carville, Angela, Mansfield, Keith G., Szinger, James J., Fischer, Will, Muldoon, Mark, Korber, Bette
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834868/
https://ncbi.nlm.nih.gov/pubmed/20173752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2089
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