Protective Efficacy of a Single Immunization of a Chimeric Adenovirus Vector-Based Vaccine against Simian Immunodeficiency Virus Challenge in Rhesus Monkeys

Rare serotype and chimeric recombinant adenovirus (rAd) vectors that evade anti-Ad5 immunity are currently being evaluated as potential vaccine vectors for human immunodeficiency virus type 1 and other pathogens. We have recently reported that a heterologous rAd prime-boost regimen expressing simian...

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Opis bibliograficzny
Główni autorzy: Barouch, Dan H., Liu, Jinyan, Lynch, Diana M., O'Brien, Kara L., La Porte, Annalena, Simmons, Nathaniel L., Riggs, Ambryice M., Clark, Sarah, Abbink, Peter, Montefiori, David C., Landucci, Gary, Forthal, Donald N., Self, Steven G., Carville, Angela, Mansfield, Keith, Goudsmit, Jaap
Format: Artigo
Język:Inglês
Wydane: American Society for Microbiology (ASM) 2009
Hasła przedmiotowe:
Vaccines and Antiviral Agents
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738237/
https://ncbi.nlm.nih.gov/pubmed/19553307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00821-09
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