Protective Efficacy of a Single Immunization of a Chimeric Adenovirus Vector-Based Vaccine against Simian Immunodeficiency Virus Challenge in Rhesus Monkeys

Rare serotype and chimeric recombinant adenovirus (rAd) vectors that evade anti-Ad5 immunity are currently being evaluated as potential vaccine vectors for human immunodeficiency virus type 1 and other pathogens. We have recently reported that a heterologous rAd prime-boost regimen expressing simian...

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Hlavní autoři: Barouch, Dan H., Liu, Jinyan, Lynch, Diana M., O'Brien, Kara L., La Porte, Annalena, Simmons, Nathaniel L., Riggs, Ambryice M., Clark, Sarah, Abbink, Peter, Montefiori, David C., Landucci, Gary, Forthal, Donald N., Self, Steven G., Carville, Angela, Mansfield, Keith, Goudsmit, Jaap
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738237/
https://ncbi.nlm.nih.gov/pubmed/19553307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00821-09
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